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Title: Electron immunocytochemical localization of enkephalin-like material in catecholamine-containing cells of the carotid body, the adrenal medulla, and in pheochromocytomas of man and other mammals. Author: Varndell IM, Tapia FJ, De Mey J, Rush RA, Bloom SR, Polak JM. Journal: J Histochem Cytochem; 1982 Jul; 30(7):682-90. PubMed ID: 6179985. Abstract: Enkephalin-like immunoreactivity has been localized to electron-dense secretory granules of cat and piglet carotid bodies and adrenal medullae, horse adrenal medulla, and also to human adrenal medulla and pheochromocytomas using a gold-labeled antibody technique performed at the electron microscopic level. The same granules were also demonstrated to exhibit dopamine-beta-hydroxylase-like immunoreactivity, which suggests a granular colocalization of amines and peptides in catecholamine-storing cells.[Abstract] [Full Text] [Related] [New Search]