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Title: Effect of disodium cromoglycate and cyclic AMP-active drugs on cytotoxic histamine release from rat mast cells. Author: Pearce FL, Clements J. Journal: Biochem Pharmacol; 1982 Jul 01; 31(13):2247-50. PubMed ID: 6181790. Abstract: Disodium cromoglycate and compounds which elevated levels of cyclic AMP in the mast cell variously inhibited cytotoxic histamine release induced by the surface active agents melittin, Tween 20 and Triton X-100. These results are inconsistent with the postulated effects of the drugs on receptor mediated calcium channels and alternative explanations of their action are considered.[Abstract] [Full Text] [Related] [New Search]