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  • Title: [The remission of extensive cancers of the mouth and oropharynx with intra-arterial polychemotherapy with vincristine, methotrexate, bleomycin, cisplatin (VMBP)].
    Author: Mika H.
    Journal: Laryngol Rhinol Otol (Stuttg); 1982 Sep; 61(9):520-3. PubMed ID: 6183545.
    Abstract:
    Initial intra-arterial chemotherapy was performed during a therapy course in 21 patients with squamous cell carcinoma of the oral cavity and oropharynx, including chemotherapy, operation, and radiation. A combination of Vincristine, Methotrexate, Bleomycin, and Cisplatin (VMBP) was administered. The aim of this initial therapy was to reduce the tumour mass. 10 patients showed complete clinical remission. In 5 of these no malignant cells could be found on histological examination of the primary site of the tumour.
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