These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Linkage analysis of nondeletion hereditary persistence of fetal hemoglobin.
    Author: Old JM, Ayyub H, Wood WG, Clegg JB, Weatherall DJ.
    Journal: Science; 1982 Feb 19; 215(4535):981-2. PubMed ID: 6186021.
    Abstract:
    Nondeletion forms of hereditary persistence of fetal hemoglobin may result from regulatory disorders of globin gene expression. The defects in two such conditions were localized by demonstrating a tight genetic linkage between the disorders and polymorphic restriction endonuclease sites within the beta-like globin gene complex. In one instance, the defect probably occurred outside the region of DNA between the epsilon- and beta-globin genes.
    [Abstract] [Full Text] [Related] [New Search]