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  • Title: beta-thromboglobulin and platelet factor 4 levels in retinal vein occlusion.
    Author: Dodson PM, Westwick J, Marks G, Kakkar VV, Galton DJ.
    Journal: Br J Ophthalmol; 1983 Mar; 67(3):143-6. PubMed ID: 6186271.
    Abstract:
    Fifty-six patients with retinal vein occlusion--35 with central and 21 with branch vein occlusion--were investigated for comparison with an age and sex matched control group. Mean levels of beta-thromboglobulin and platelet factor 4 were significantly higher (p less than 0.001) in both the group with central and the group with branch retinal vein occlusion than in the control group. A significant increase of beta-thromboglobulin (p less than 0.001) was also found in the retinal vein occlusion group in those patients who were not hyperlipidaemic or diabetic (n = 39). Weak correlations were found between levels of lipoprotein cholesterol and plasma beta-thromboglobulin. Increased platelet aggregation may contribute to the aetiology of retinal vein occlusion.
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