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  • Title: [Effect of dextran 60,000(D 60) and hydroxyethyl starch 450,000 (HES 450) on lymphocyte transformation].
    Author: Khosropour R, Cerni C, Lackner F, Watzek C.
    Journal: Anaesthesist; 1983 Jan; 32(1):25-7. PubMed ID: 6189413.
    Abstract:
    Lymphocytes of volunteers were recovered, isolated and H3 thymidine incorporation was measured in the presence of D 60 and HES 450 with and without PHA. Without mitogen dextran caused only a marginal increase of incorporation whereas HES brought about no change. When PHA-stimulation was used, both compounds seemed not to influence H3-thymidine incorporation. It is concluded that in vitro even in molar concentrations corresponding to clinical haemodilution these solutions appear not to suppress lymphocytic activity.
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