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  • Title: The effect of surgery on the renal excretion of beta 2-microglobulin.
    Author: Walenkamp GH, Vree TB, Guelen PJ, Jongman-Nix B.
    Journal: Clin Chim Acta; 1983 Mar 28; 129(1):27-37. PubMed ID: 6189646.
    Abstract:
    Surgical trauma causes an increase in the renal excretion rate of beta 2-microglobulin whilst creatinine excretion is not influenced. The increase in the renal excretion rate of beta 2-microglobulin is probably the result of an increased release of beta 2-microglobulin by the cells which exceeds a maximum in the active tubular reabsorption of the compound by the proximal tubule cell. The renal excretion of beta 2-microglobulin is proportional to the relative clinical trauma score.
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