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  • Title: Urinary N-acetyl-beta-D-glucosaminidase and beta 2-microglobulin in 'itai-itai' disease.
    Author: Nogawa K, Yamada Y, Honda R, Tsuritani I, Ishizaki M, Sakamoto M.
    Journal: Toxicol Lett; 1983 May; 16(3-4):317-22. PubMed ID: 6190270.
    Abstract:
    N-acetyl-beta-D-glucosaminidase (NAG) activity in urine was measured in patients with 'itai-itai' disease, from chronically advanced cadmium poisoning. Elevation of NAG activity, however, was not so marked as that of beta 2-microglobulin (beta 2-MG) in the urine of patients and suspected patients. We conclude that the beta 2-MG test is more valuable than the NAG test for evaluating the severity of the renal tubular damage in chronically advanced cadmium (Cd) poisoning.
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