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  • Title: [Effectiveness of dsRNA as an interferon inducer in the intramuscular infection of mice with rabies street virus].
    Author: Gribencha SV, Nosik NN, Ershov FI, Barinskiĭ IF.
    Journal: Vopr Virusol; 1983; (2):232-5. PubMed ID: 6191440.
    Abstract:
    A protective effect of double-stranded RNA as interferon inducer was demonstrated in mice inoculated intramuscularly with street rabies virus. A significant degree of protection was observed when the inducer was inoculated intracerebrally and at the site of virus inoculation both 24 h before and 4 and 24 h after infection. Inoculation of the inducer into the muscle opposite to the infected leg and subcutaneously into the back proved to be ineffective. It was established that rabies infection could be arrested with the interferon inducer depending on the site of its inoculation.
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