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Title: [Effects of the bronchial artery infusion of peplomycin (PEP) and mitomycin C (MMC) in lung cancer--comparison with single administration of PEP or MMC]. Author: Yokoyama K, Takashima T, Nozaki M, Kaito S, Shimomura T, Takeuchi A, Kurokawa A. Journal: Gan To Kagaku Ryoho; 1983 Aug; 10(8):1817-22. PubMed ID: 6192772. Abstract: Effects of BAI with PEP 30 mg+MMC 10 mg on 26 patients with lung cancer were evaluated in comparison with 34 cases treated with single PEP or MMC. Histopathological findings of the cases treated with PEP+MMC and PEP alone showed more effective results than that of MMC alone. The tumor decreased rate on the chest X-ray film of the cases treated with PEP+MMC was highest and the cavity formation was also typical in the cases with PEP+MMC and PEP alone. The side effects of the cases with PEP+MMC were able to reduce markedly to about 50% compared with single administration of PEP or MMC; however pulmonary fibrosis and necrotizing bronchitis were noted in 8%.[Abstract] [Full Text] [Related] [New Search]