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  • Title: [Fractionated short-time-afterloading with high dose rates in ambulant treatment of inoperable cancer of the uterine corpus].
    Author: Kucera H, Unel N, Weghaupt K.
    Journal: Geburtshilfe Frauenheilkd; 1983 Jul; 43(7):456-60. PubMed ID: 6194042.
    Abstract:
    In the period of 1.6. 1980 to 31.12. 1981 110 patients with inoperable endometrial carcinoma were treated by fractionated short-time afterloading with high dose rates (Buchler, Germany; Iridium-192) or with conventional intracavitary radium-therapy (low dose rates). First clinical results concerning 12-months-survival rate and the observed reactions of bladder and rectum in the afterloading-group and in the radium-group are represented. The one-year-survival rate and the side effects in the afterloading-group were comparable to those in the radium-group. 35 out of 40 patients (87,5%) with stage I of the disease treated with Iridium-192 were alive after one year, as compared to 46 out of 59 (77,9%) patients treated with Radium. The rate of radiation side effects showed no statistically significant difference in both groups. In the afterloading-group a hospitalization was not necessary, because anesthesia was not performed during short-time irradiation.
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