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  • Title: Changes in serum proteins following implantation of pacemakers.
    Author: Podhradská M, Vajó J, Andrasina J.
    Journal: Cor Vasa; 1983; 25(5):372-80. PubMed ID: 6197229.
    Abstract:
    The change in the protein concentration in blood serum was investigated after implantation of a pacing system with epoxide surface (group A, 20 patients) or metallic case (group B, 9 patients). The response to surgical intervention was equal in both groups. In the first period following operation the acute phase reaction took place in terms of increasing concentrations of alpha-globulins, especially alpha 1-acid glycoprotein, alpha 1-antitrypsin, ceruloplasmin, haptoglobin, and beta 1A/C-globulin, Simultaneously, a decrease in prealbumin, albumin, beta-globulin, in particular haemopexin and transferin concentration appeared. As for immunoglobulins, a decrease in IgG and increase in IgA and IgM globulins was observed. In the course of a longer period of time following implantation (group B--three months; group A--two years) a decrease of almost all investigated proteins was observed with exception of increased IgA globulin and transferin in group A.
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