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Title: Mutual stimulation by phosphatidylinositol-4-phosphate and myelin basic protein of their phosphorylation by the kinases solubilized from rat brain myelin. Author: Deshmukh DS, Kuizon S, Brockerhoff H. Journal: Life Sci; 1984 Jan 16; 34(3):259-64. PubMed ID: 6198580. Abstract: Myelin basic protein and phosphatidylinositol-4-phosphate are phosphorylated in vitro by ATP and solubilized rat brain myelin. When both substrates are present together, the rate of phosphorylation of each is increased about eight-fold. It appears likely that the phosphate turnover of myelin basic protein and of phosphatidylinositol-4-phosphate are coupled in vivo.[Abstract] [Full Text] [Related] [New Search]