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  • Title: Genetic amniocentesis in seventy twin pregnancies.
    Author: Librach CL, Doran TA, Benzie RJ, Jones JM.
    Journal: Am J Obstet Gynecol; 1984 Mar 01; 148(5):585-91. PubMed ID: 6199976.
    Abstract:
    Genetic amniocenteses were performed in 70 twin pregnancies over an 11-year period. Both sacs were successfully sampled in 49 of 62 patients (79%). The success rate was decreased (68%) with two placentas (anterior and posterior) and was improved with gestational age greater than or equal to 17 weeks (88%) and with ultrasound visualization of the septum (86%). Of three spontaneous abortions, two were attributed to amniocentesis (chorioamnionitis). When twin pregnancy is diagnosed in a patient with an indication for genetic amniocentesis, a careful reevaluation and discussion of risk factors with the couple are recommended.
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