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  • Title: A probe of the human plasmin-alpha 2-macroglobulin interaction utilizing monoclonal antibodies to human plasmin.
    Author: Cummings HS, Castellino FJ.
    Journal: Ann N Y Acad Sci; 1983; 421():143-8. PubMed ID: 6202187.
    Abstract:
    These experiments have shown that alpha 2M may have a bait region capable of accommodating proteases of a far greater molecular weight than previously recognized, since antibody-plasmin complexes apparently become entrapped. In the case of large proteases, however, it now appears that a portion of these molecules is not enclosed. Clearly, in the case of plasmin, the K1-4 region remains outside the molecular trap.
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