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  • Title: Fatal connective tissue disease with antinuclear antibodies following PUVA therapy.
    Author: Bruze M, Krook G, Ljunggren B.
    Journal: Acta Derm Venereol; 1984; 64(2):157-60. PubMed ID: 6203306.
    Abstract:
    Antinuclear antibodies with a nucleolar staining pattern appeared in a psoriasis patient during PUVA therapy. No antinuclear antibodies were found after the termination of PUVA but they reappeared one year later together with symptoms consistent with a connective tissue disease. The course was fatal and the clinical and the laboratory investigations suggested a scleroderma-like syndrome.
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