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  • Title: [Intravesical chemotherapy for superficial bladder tumors].
    Author: Ohmori H.
    Journal: Gan To Kagaku Ryoho; 1984 Aug; 11(8):1557-62. PubMed ID: 6206797.
    Abstract:
    Intravesical chemotherapy is one of the most effective treatments for superficial bladder tumors. Recent progress in the development of chemotherapeutic agents has provided a variety of compounds of potential benefit for intravesical administration in cases of superficial bladder tumors, including thio-TEPA, MMC, carboquone, adriamycin, FT-207, cytosine arabinoside and bleomycin, and the in therapeutic effectiveness has been reported. We selected adriamycin, because it is considered suitable for intravesical instillation. A 68% effectiveness has been experienced for instillation repeated six to nine times (adriamycin 50 mg/normal saline 30 ml) and side effects occurred in 23% of patients. Intravesical chemotherapy has also been attempted to prevent recurrence after conservative therapy but these modalities still seem to need further study.
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