These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: A monoclonal antibody to human transferrin receptor which inhibits erythroid differentiation of human leukemic K-562 cells.
    Author: Gambari R.
    Journal: Boll Soc Ital Biol Sper; 1984 Jun 30; 60(6):1283-5. PubMed ID: 6206881.
    Abstract:
    In this paper we demonstrate that the 42/6 monoclonal antibody to human transferrin receptor (1) inhibits erythroid differentiation of human leukemic K-562 cells without affecting cell proliferation. Erythroid induction was monitored by benzidine-staining of K-562 cell suspensions and hemoglobin accumulation by cellulose acetate gel electrophoresis of post-mitochondrial cell lysates (4,5). Our results suggest that erythroid differentiation and cell growth require a different number of transferrin receptors.
    [Abstract] [Full Text] [Related] [New Search]