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  • Title: Combination chemotherapy for metastatic urinary bladder cancer with 5-FU, vincristine, bleomycin, cyclophosphamide, mitomycin, and methotrexate.
    Author: Kubota Y, Shuin T, Miura T, Moriyama M, Fukushima S, Shiozaki H, Ooshima H.
    Journal: Cancer Treat Rep; 1984 Sep; 68(9):1167-8. PubMed ID: 6206946.
    Abstract:
    Twenty-two patients with advanced primary bladder cancer with metastatic lesions were treated with a combination of 5-FU, vincristine, bleomycin, mitomycin, and methotrexate. Complete and partial responses were achieved in two (9%) and five (23%) patients, respectively. The overall response rate was 32%. The major toxic effects were myelosuppression and mild gastrointestinal symptoms.
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