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Title: The 3'-untranslated sequence of human skeletal muscle alpha-actin mRNA. Author: Gillespie G, Lloyd J, Hopkinson D, Edwards Y. Journal: J Muscle Res Cell Motil; 1984 Aug; 5(4):457-64. PubMed ID: 6207203. Abstract: A human actin cDNA clone pGF3 isolated from a fetal skeletal muscle cDNA library is described. The insert cDNA is homologous to skeletal muscle alpha-actin as judged by restriction mapping and nucleotide sequencing. The recombinant contains a substantial portion of the coding and the complete 3'-untranslated region. Comparison of the 3' ends of human and rat skeletal muscle and human cardiac alpha-actins reveals little homology between different types of actin genes in man but marked conservation of this region in the skeletal muscle actins of man and rat.[Abstract] [Full Text] [Related] [New Search]