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  • Title: Decrease of plasma fibronectin concentration following infusion of a gelatin-based plasma substitute in man.
    Author: Brodin B, Hesselvik F, von Schenck H.
    Journal: Scand J Clin Lab Invest; 1984 Oct; 44(6):529-33. PubMed ID: 6207588.
    Abstract:
    Intravenous infusion of 500 ml of a gelatin-based plasma substitute, Haemaccel, given to healthy volunteers, resulted in a significant decrease of the immunoreactive plasma fibronectin concentration 48 h and 72 h after infusion. One hour after infusion, the ability of fibronectin to bind gelatin was inhibited with a gradual recovery within 48 h. A dextran based plasma substitute, Macrodex, did not have this effect on plasma fibronectin.
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