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  • Title: [Effect of rearing conditions on nucleic acid synthesis in the brain of rats of different genotypes].
    Author: Vitvitskaia LV, Panfilov AD.
    Journal: Nauchnye Doki Vyss Shkoly Biol Nauki; 1984; (8):26-31. PubMed ID: 6207862.
    Abstract:
    The incorporation of [3H]thymidine into DNA and of [14C]uridine into RNA has been investigated in different areas of brain and in liver of inbred August rats, non-inbred Wistar rats and hybrids between male wild-type and female Wistar rats which were kept either under normal conditions or under intensive sensory stimulation at different age. DNA metabolism has been found to display tissue, regional, age-dependent and interlinear differences. Sensory stimulation influences considerably the synthesis of nucleic acids which is maximal at early ontogenesis stages and in the brain of hybrid animals.
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