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  • Title: Surgery and chemotherapy. A new method of treatment for squamous cell bronchial carcinoma.
    Author: Raut Y, Huu N, Clavier J, Guillerm D, Barra JA.
    Journal: J Thorac Cardiovasc Surg; 1984 Nov; 88(5 Pt 1):754-7. PubMed ID: 6208433.
    Abstract:
    Between April, 1981, and December, 1982, 32 patients with squamous cell bronchial carcinoma were treated with a chemotherapy regimen followed by operation. The preoperative chemotherapeutic agents used were cisplatin, bleomycin, and mitomycin C. A thoracotomy was performed 3 to 4 weeks after the last day of the last treatment. Of the 29 undergoing resection, three (10.3%) had no tumor cells in the resected specimen and four (12.5%) had only a few neoplastic microcenters in tissue necrosis or fibrosis. We suggest that the use of this new chemotherapy combination with surgical resection provides excellent palliation, increases resectability, and has a potential for increasing the cure rate in squamous cell carcinoma of the lung.
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