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  • Title: [Immunological analysis of the chronological sequence of the shift in the antigenic determinants of influenza virus A (H1N1) hemagglutinins].
    Author: Isaeva EI, Rovnova ZI, Belkina TS.
    Journal: Vopr Virusol; 1984; 29(4):423-7. PubMed ID: 6208689.
    Abstract:
    The study of the antigenic composition of influenza A (H1N1) viruses of two circulation periods, 1933-1957 and 1977-1981, by the method of selective adsorption of highly active antihemagglutinating sera revealed the ways of antigenic variability of drift variants. The antigenic composition of the hemagglutinin of H1N1 viruses of the second circulation period was found to be similar to that of H1N1 viruses isolated in 1950-1953.
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