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  • Title: Safety of cimetidine.
    Author: Kruss DM, Littman A.
    Journal: Gastroenterology; 1978 Feb; 74(2 Pt 2):478-83. PubMed ID: 620916.
    Abstract:
    Our review of published material, manufacturer's files, and submissions to the United States Food and Drug Administration indicates that cimetidine is safe for short term use (up to 8 weeks). This judgment is based on a total experience with over 3000 patients. Clinically insignificant elevations of serum creatinine occur in a high percentage of patients, persisting until the end of therapy, then disappearing. Gynecomastia occurred in some patients on long term therapy.
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