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  • Title: The action of substance P on contraction, inositol phospholipids and adenylate cyclase in rat small intestine.
    Author: Watson SP.
    Journal: Biochem Pharmacol; 1984 Dec 01; 33(23):3733-7. PubMed ID: 6210088.
    Abstract:
    The actions of substance P and eledoisin on contraction, [3H]inositol 1-phosphate and cAMP formation in the rat ileum have been compared. Eledoisin was considerably more potent than substance P on both contraction and [3H]inositol 1-phosphate production. Neither peptide altered the cAMP levels in the tissue. These results are discussed in relation to the substance P receptor sub-type present in the rat ileum, and its second messenger.
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