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  • Title: Ipratropium bromide and fenoterol by aerosolized solution.
    Author: Jenkins CR, Chow CM, Fisher BL, Marlin GE.
    Journal: Br J Clin Pharmacol; 1982 Jul; 14(1):113-5. PubMed ID: 6213250.
    Abstract:
    Ipratropium bromide (0.5 mg) and fenoterol (2 mg) produced equivalent peak bronchodilatation between 1 and 2 h after administration to eight patients with chronic partially reversible airways obstruction. The duration of action compared with saline was 6 h for ipratropium and 4 h for fenoterol. Both drugs in combination produced greater bronchodilatation than either drug alone. The increase in FVC was disproportionately greater than FEV1 with both drugs and saline, suggesting relief of obstruction of small airways.
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