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  • Title: [2-Aminopurine, analog of adenine, induces a nonmutagenic repair mechanism acting upon UV lesions of double-stranded DNA in E. coli].
    Author: Maenhaut-Michel G, Caillet-Fauquet P.
    Journal: C R Seances Soc Biol Fil; 1982; 176(3):406-10. PubMed ID: 6215107.
    Abstract:
    The survival of ultraviolet light (UV)--irradiated lambda phage is increased when host bacteria are grown in the presence of the base analogue 2-amino-purine (2 AP) prior infection. This increase in survival, which we call "2-AP-reactivation", has the following characteristics: (1) it is not accompanied by mutagenesis; (2) it occurs in recA- and lexA- bacterial mutants; (3) is abolished in the polA- mutant (deficient in DNA polymerase I).
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