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  • Title: Histamine-induced inhibition of lymphocyte proliferation and lysosomal enzyme release from polymorphs may not be mediated via H1- or H2-receptors.
    Author: Vickers MR, Milliner K, Martin D, Ganellin CR.
    Journal: Agents Actions; 1982 Dec; 12(5-6):630-4. PubMed ID: 6219553.
    Abstract:
    Histamine, selective histamine H1- and H2-receptor agonists, and chemical analogues of these compounds lacking activity at histamine receptors, were tested as inhibitors of phytohaemagglutinin-induced human lymphocyte proliferation and zymosan-induced release of lysosomal enzymes from human polymorphs. No correlation was found between their inhibitory potency in these systems and their relative activity at histamine H1- or H2-receptors.
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