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  • Title: Thymoxamine versus pilocarpine in the reversal of phenylephrine-induced mydriasis.
    Author: Saheb NE, Lorenzetti D, East D, Salpeter-Carlton S.
    Journal: Can J Ophthalmol; 1982 Dec; 17(6):266-7. PubMed ID: 6219733.
    Abstract:
    Thymoxamine, a selective alpha-adrenergic blocker, was compared with pilocarpine in 19 patients for its reversal of phenylephrine-induced mydriasis. Both agents constricted the pupil to its original size in less than half an hour, and thymoxamine's half-life was twice that of pilocarpine's. The advantages of thymoxamine miosis, particularly in patients with narrow angles, are discussed.
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