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  • Title: The comparative activity of norfloxacin with other antimicrobial agents against Gram-positive and Gram-negative bacteria.
    Author: Corrado ML, Cherubin CE, Shulman M.
    Journal: J Antimicrob Chemother; 1983 Apr; 11(4):369-76. PubMed ID: 6222023.
    Abstract:
    Norfloxacin (MK0366) displayed appreciable activity against the great majority of Gram-negative and Gram-positive bacteria. The minimum inhibitory concentration for 90% of isolates (MIC90) of the Enterobacteriaceae was 0.5 mg/l or less while for Campylobacter, Neisseria, Haemophilus MIC90s were 0.25 mg/l or less. Norfloxacin was also among the most active drugs tested against methicillin susceptible and resistant Staphylococcus aureus, Staph. epidermidis, enterococci and Pseudomonas aeruginosa with MIC90s between 0.5 and 4 mg/l.
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