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  • Title: [Clinical studies of piperacillin in the field of obstetrics and gynecology].
    Author: Seiga K, Sugiyama Y, Yamaji K.
    Journal: Jpn J Antibiot; 1982 Oct; 35(10):2354-63. PubMed ID: 6223154.
    Abstract:
    We studied piperacillin (PIPC) clinically to evaluate its utility and safety, and obtained the following results. PIPC was given at a daily dose of 1 approximately 4 g for 3 approximately 10 days by bolus injection or dripping infusion to 18 patients with various infections in the field of obstetrics and gynecology. Four of 5 cases with intrauterine infection, 2 of 3 cases with focus infection of uterine cancer, 2 cases with perinatal intrauterine infection, 2 of 6 cases with adnexal infection and 2 cases with vulvar infection proved to respond effectively. The overall efficacy rate was 66.7%. No side effect or abnormal laboratory findings were observed except for 1 case with rash.
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