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  • Title: The "concrete" histological diagnosis of cerebral tumours of neuroectodermic origin.
    Author: Papilian VV, Morar M.
    Journal: Morphol Embryol (Bucur); 1983; 29(2):109-16. PubMed ID: 6224078.
    Abstract:
    The "concrete" histological criteria for establishing the benignity or malignancy of cerebral tumours of neuroectodermic origin (gliomas and medulloblastomas, respectively granulocytomas) may be thus synthetized: 1) the benign tumours have a fibrocellular structure, the neoplastic cells being relatively monomorphous; vascular hyperplasia is absent, as well as necrotic and hemorrhagic foci; 2) the malignant tumours are hyper- and polymorphocellular, the fibrillar component being reduced or absent; vascular hyperplasia as well as the presence of necrotic and/or hemorrhagic foci is a constant characteristic; the tumoral cells often infiltrate the perivascular spaces.
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