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  • Title: ATPase activities and lipid peroxidation in rat cerebral cortex synaptosomes.
    Author: Gilbert JC, Sawas AH.
    Journal: Arch Int Pharmacodyn Ther; 1983 Jun; 263(2):189-96. PubMed ID: 6224471.
    Abstract:
    ATPase activities and lipid peroxidation as measured by malonaldehyde formation in rat cerebral cortex synaptosomes depend on the time of incubation of the tissue. ATPase activities decreased but lipid peroxidation activity increased with increasing incubation periods. Effects of catechol- and non-catechol molecules on lipid peroxidation in synaptosomes have been determined. Drugs previously shown to stimulate ATPases inhibited lipid peroxidation. It seems likely that close relationships exist between stimulation of ATPase activities and inhibition of lipid peroxidation.
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