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  • Title: Fructose 2,6-bisphosphate in livers of genetically obese rats.
    Author: Hue L, van de Werve G, Jeanrenaud B.
    Journal: Biochem J; 1983 Sep 15; 214(3):1019-22. PubMed ID: 6226282.
    Abstract:
    Livers of genetically obese (fa/fa) rats, starved for 24 h, contained more fructose 2,6-bisphosphate, glucose 6-phosphate, fructose 6-phosphate and glycogen, and more pyruvate kinase and phosphofructokinase 2 activities, than livers of control lean rats. These changes may be explained in terms of cyclic AMP concentration, which was decreased in livers of obese starved rats.
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