These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Heat-sensitive radiation damage in single-stranded DNA irradiated in a bacterial extract.
    Author: Lafleur MV, Pluijmackers-Westmijze EJ, Loman H.
    Journal: Int J Radiat Biol Relat Stud Phys Chem Med; 1983 Nov; 44(5):483-8. PubMed ID: 6227576.
    Abstract:
    The effect of heat treatment (45 degrees C) on gamma-irradiated biologically active single-stranded phi X174 DNA, dissolved in a bacterial extract, was studied. The results show that under these circumstances heat-sensitive damage is found, which is absent after irradiation in pure buffer. The damage is non-lethal and probably becomes an apurinic/apyrimidinic site, which is lethal, upon the post-irradiation heat treatment. Prolonged heating converts it into a break. The amount of the initial damage depends on the conditions of irradiation.
    [Abstract] [Full Text] [Related] [New Search]