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  • Title: Regulation of IgE antibody synthesis.
    Author: Konig W, Pfeiffer P, Theobald K, Szperalski B, Voshaar T, Hess KH, Bohn A.
    Journal: Allergol Immunopathol (Madr); 1983; 11(4):277-84. PubMed ID: 6228129.
    Abstract:
    It is well established that IgE-antibodies against allergens are involved in allergic diseases. Thus, the regulation of IgE antibody synthesis appears to be a fundamental approach to its treatment. The mechanisms of the IgE-antibody response are somehow different from IgG production. It appears that the immunocompetent cells involved are distinct and exert a different susceptibility with regard to IgE- and IgG antibody production. A more precise under-standing of the cellular processes involved in IgE-antibody production will lead to novel immunotherapeutic approaches of allergic disease processes.
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