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  • Title: Morphophysiological studies in experimental myocardial aggressions with isoproterenol. Note I. Morphological aspects.
    Author: Laky D, Constantinescu S, Filipescu G, Ratea E, Zeană C.
    Journal: Morphol Embryol (Bucur); 1983; 29(4):273-7. PubMed ID: 6228730.
    Abstract:
    The morphopathogenesis of lesions induced by high doses of isoproterenol injected for 1-7 days and 1-3 months is dynamically studied in groups of Wistar rats and guinea pigs. The disseminated myocardial necroses induced were of a hypoxic nature. By cicatricial substitutions, lesions of cardiosclerosis similar to those observed in pheochromocytoma cases were obtained.
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