These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Familial focal segmental glomerulosclerosis.
    Author: Tejani A, Nicastri A, Phadke K, Sen D, Adamson O, Dunn I, Calderon P.
    Journal: Int J Pediatr Nephrol; 1983 Dec; 4(4):231-4. PubMed ID: 6229501.
    Abstract:
    We have observed the nephrotic syndrome in more than one sibling in three unrelated hispanic families. The histological lesion in the involved children was either focal segmental glomerulosclerosis or IgM nephropathy evolving into focal sclerosis. Tissue typing revealed the presence of HLA DRw8 in six out of eight patients. The frequency of this antigen in our patients, when compared with its frequency in a group of unrelated normal hispanic children was highly significant (p less than 0.0001). Our study suggests that there may be a genetic predilection towards developing focal segmental glomerulosclerosis.
    [Abstract] [Full Text] [Related] [New Search]