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  • Title: [Levels of glutathione and anaerobic glycolysis in the kidney and liver of rats treated with chloroethanol].
    Author: Rinaudo MT, Curto M, Bruno R.
    Journal: Boll Soc Ital Biol Sper; 1983 Nov 30; 59(11):1583-9. PubMed ID: 6230087.
    Abstract:
    Chloroethanol administration produces in rats a strong fall of glutathione levels in liver and kidney tissues. In liver, such a modification does not imply alterations in the levels of glucose, glucose-6-phosphate, fructose-6-phosphate, fructose-1,6-biphosphate, lactate and pyruvate and in the glycolytic activity. In kidney, the glycolytic activity does not result modified, while it appears a reduction in levels of glucose, glucose-6-phosphate, fructose-1,6-biphosphate and triose phosphates and a remarkable increase of pyruvate. The administration of chloroethanol produces a strong fall of glutathione in the soluble and nuclear fractions of liver and in the soluble and mitochondrial fractions of kidney.
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