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  • Title: A case of selective IgM deficiency: isotype-specific suppressor T lymphocytes.
    Author: Matsushita S, Inoue T, Okubo H.
    Journal: Jpn J Med; 1984 May; 23(2):149-51. PubMed ID: 6233438.
    Abstract:
    A case of selective IgM deficiency with giant leiomyoma of the stomach in a 66-year-old male is reported. Peripheral blood mononuclear cells from the patient synthesized only a small amount of IgM in the presence of pokeweed mitogen (PWM) in vitro. Co-culture of counterpart lymphocytes from the patient and a disease-free individual revealed that increased activity of IgM-specific suppressor T lymphocytes led to a IgM deficiency in this case.
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