These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effect of aliphatic monoamines on motor activity of mice: no direct interaction with dopaminergic D2 receptor.
    Author: Widy-Tyszkiewicz E, Członkowski A.
    Journal: Pol J Pharmacol Pharm; 1983; 35(6):467-72. PubMed ID: 6234517.
    Abstract:
    The effect of butylamine, pentylamine and hexylamine on spontaneous locomotor activity of mice was evaluated in the presence or absence of drugs affecting monoaminergic neurons. Pentylamine and hexylamine produced similar effects (stimulation after low, inhibition after high doses), while butylamine action was weak. Depression of locomotor activity produced by combined treatment with alpha-methyl-tyrosine, reserpine and dopa was counteracted by pentylamine and hexylamine; they did not produce such an effect in the absence of dopa. The amines did not displace 3H-spiperone specifically bound to striatal membranes.
    [Abstract] [Full Text] [Related] [New Search]