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  • Title: Exacerbation of myasthenia gravis after removal of a thymoma having a membrane phenotype of suppressor T cells.
    Author: Kuroda Y, Oda K, Neshige R, Shibasaki H.
    Journal: Ann Neurol; 1984 Apr; 15(4):400-2. PubMed ID: 6234854.
    Abstract:
    We describe a case of myasthenia gravis associated with a thymoma having a membrane phenotype of suppressor T cells, as defined by monoclonal antibodies. Thymectomy resulted in exacerbation of the disease, a drastic increase in serum acetylcholine receptor-antibody titer, and a decrease of the circulating suppressor T cell population. The findings indicate that the etiopathogenic relationship between the thymus and myasthenia gravis is variable and complex.
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