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  • Title: Experimental ampicillin glomerulonephropathy.
    Author: Wright NG, Nash AS.
    Journal: J Comp Pathol; 1984 Jul; 94(3):357-61. PubMed ID: 6236237.
    Abstract:
    Eighteen dogs were given repeated doses (between 4 and 19) of ampicillin (7 mg per kg intramuscularly on 3 days a week). Fifteen of the dogs developed a subclinical glomerulonephropathy characterized by mesangial hypercellularity. While only 9 of the 18 dogs showed electron-dense deposits in the mesangium, 14 dogs had glomerular deposits of IgG and 11 of these had C3 deposits also.
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