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  • Title: Altered property of sarcoplasmic Ca-ATPase from vitamin E-deficient dystrophic rabbit is associated with the protein and not the lipid component.
    Author: Patipaporn K, Wilairat P, Komaratat P.
    Journal: Biochem Int; 1983 Mar; 6(3):335-8. PubMed ID: 6236817.
    Abstract:
    The effects of temperature on reconstituted sarcoplasmic Ca-ATPase preparations from vitamin E-deficient dystrophic and control rabbits were studied. Delipidated Ca-ATPase from vitamin E-deficient sarcoplasmic reticulum (SR) reconstituted with lipid of control SR exhibited properties similar to preparations reconstituted with lipid of vitamin E-deficient SR, namely low Ca-ATPase activity and a linear Arrhenius plot of enzyme activity. On the other hand, delipidated control SR Ca-ATPase reconstituted with lipid of vitamin E-deficient SR showed a reduction in activity but retained the discontinuity in the Arrhenius plot. These results indicated that the altered property of sarcoplasmic Ca-ATPase from vitamin E-deficient dystrophic rabbit was associated with the protein and not the lipid component.
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