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  • Title: [Computer tomographic determination of left ventricular muscle mass].
    Author: Klose KJ, Düber C, Thelen M.
    Journal: Z Kardiol; 1984 Jul; 73(7):442-54. PubMed ID: 6237507.
    Abstract:
    Left ventricular muscle mass LVMM) was determined by computed tomography in 19 dogs (33 in vivo and 19 postmortem studies). CT values obtained with 4 models were compared with the actual LVMM at autopsy. Excellent correlation was achieved by volumetric analysis (model A; r = 0.95-0.96). Accurate assessment of LVMM was also obtained using a two-axis method (model B), an area-length method (model C), or a representative cross-sectional volume (model D). There was no significant difference between in vivo and postmortem studies. We conclude that CT can provide reliable estimates of LVMM in vivo. Volumetric analysis is not dependent on mathematical models of the left ventricle. However, this method is very time-consuming. The other CT-models are simple enough to permit clinical application. In comparison with other experimental and clinical methods of LVMM quantitation, CT is superior to chest X-ray, ECG, VCG, and M-mode echocardiography, while similar good results can be obtained with two-dimensional echocardiography as well as conventional and digital angiocardiography.
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