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  • Title: [Allergic contact eczema caused by isothiazolin-3-one derivatives].
    Author: Foussereau J, Brändle I, Boujnah-Khouadja A.
    Journal: Derm Beruf Umwelt; 1984; 32(6):208-11. PubMed ID: 6241142.
    Abstract:
    Observations concerning contact dermatitis to derivatives of isothiazolin-3-one are reported. A systematic review of the literature of previously published cases is reported. A verified contact dermatitis to benzisothiazolin-3-one of a laborer in a rubber factory is discussed. Another case of occupational dermatitis concerns an allergy to a commercial product, containing 2-n-octyl-4-isothiazolin-3-one as a preservative and utilized by shoe factory workers. Additionally, cases of an allergy to cosmetic preparations, containing a mixture of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, are elaborated.
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