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  • Title: T cell clones and hybridomas as probes for the analysis of the syngeneic mixed leukocyte reaction.
    Author: Dos Reis GA, Glimcher LH, Shevach EM.
    Journal: Behring Inst Mitt; 1983 May; (72):59-66. PubMed ID: 6242340.
    Abstract:
    We have prepared short term T cell lines, long term T cell lines from soft agar colonies, and SMLR specific T cell hybridomas. Analysis of these populations has shown that the SMLR responsive T cell population is not specific for a foreign serum component, but rather represents a T cell population which can be polyclonally activated by self-Ia antigens. It is likely that some antigen specific cells are found within this autoreactive subpopulation.
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