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  • Title: Direct immunoelectron microscopy of transmissible gastroenteritis virus with immunoglobulins G and A and guinea pig complement.
    Author: Jensen MT, Kemeny LJ, Stone SS, Ritchie AE.
    Journal: Am J Vet Res; 1980 Jan; 41(1):136-9. PubMed ID: 6244762.
    Abstract:
    Porcine colostral immunoglobulin (Ig)G and IgA, isolated from transmissible gastroenteritis virus-infected sows, were compared by direct immunoelectron microscopy. It was estimated, using antibodies with a less than a twofold difference in virus-neutralizing activity, that IgG was 500 times more efficient than was IgA for coating transmissible gastroenteritis virions. Guinea pig complement enhanced the antibody coating with IgG, but did not increase virus-neutralizing activity of IgG or IgA.
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