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  • Title: Cholecystokinin receptors in the brain: characterization and distribution.
    Author: Saito A, Sankaran H, Goldfine ID, Williams JA.
    Journal: Science; 1980 Jun 06; 208(4448):1155-6. PubMed ID: 6246582.
    Abstract:
    Specific cholecystokinin binding sites in particulate fractions of rat brain were measured with iodine 125-labeled Bolton-Hunter cholecystokinin, a cholecystokinin analog that has full biological activity. Binding was detected in brain regions known to contain immunoreactive cholecystokinin. Binding was saturable, reversible, of high affinity (dissociation constant, 1.7 x 10(-9) M), and was inhibited by cholecystokinin analogs but not by unrelated hormones.
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